Vaginal Cancer

What is Vaginal Cancer?

The vagina is a three- to four-inch tube that goes from the cervix (bottom section of the uterus or womb) to the vulva (the outside part of female genitals). According to the American Cancer Society, 5,100 women are diagnosed with vaginal cancer each year in the United States. They may vary in different types of vaginal cancer such as follows:

The types of vaginal cancer:

Squamous cell carcinoma : Most vaginal cancers are squamous cell cancers, which start in the vagina lining. These cancers develop slowly, sometimes over many years. Often they begin as vaginal intraepithelial neoplasia (VAIN), which is a precancerous condition. VAIN is found most often in women who have had hysterectomies (removal of the uterus), cervical cancer or cervical precancer.

Adenocarcinoma : This cancer starts in the gland cells of the vagina and is most often found in women over 50. A subtype called clear cell adenocarcinoma is found in younger women whose mothers took the drug DES when they were pregnant.

Melanoma : This type of vaginal cancer starts in the cells that give the skin color.

Sarcoma : A small number vaginal cancers are sarcomas, which start within the wall of the vagina. The most common type is rhabdomyosarcoma, which usually is found in children.

Sometimes cancer that begins in other parts of the body spreads (metastasizes) to the vagina. When this happens, the cancer is named for the part of the body where it started. Cancer of the cervix and vagina is called cervical cancer. Cancer of the vulva and vagina is called vulvar cancer. 

Risk Factors:

Anything that increases your chance of getting vaginal cancer is a risk factor.

These include:

DES (diethylstilbestrol): This drug was given between 1940 and 1971 to some pregnant women to help them not have a miscarriage (lose the baby).

Vaginal adenosis: In some women, especially those whose mothers took DES, the cells in the vagina change from squamous cells to endometrium (or glandular) cells.

Not everyone with risk factors gets vaginal cancer. However, if you have risk factors, you should discuss them with your doctor.
In rare cases, vaginal cancer can be passed down from one generation to the next. Genetic counseling may be right for you. Visit our genetic testing page to learn more.

What happens after you come at ACH for all kind of vaginal cancer?

When you come to ACH for vaginal cancer care, a team of experts focuses on you. These nationally known physicians customize your therapy to include the most advanced vaginal cancer treatments with the least impact on your body.
Your care team works closely together, communicating and collaborating often, to be sure you receive the most comprehensive and efficient care. The group may include surgical, medical, radiation and gynecological oncologists; surgeons and reconstructive surgeons; diagnostic radiologists and pathologists. A specially trained support staff joins them in delivering your care for vaginal cancer.

ACH treats more women each year with complex type of cancer, than most oncologists in the nation. Giving us a level of experience and expertise that is rare, and translates to more successful outcomes for many women with vaginal cancer.
Surgery often is one of the methods used to treat vaginal cancer. Our skilled surgeons – who include some of the top reconstructive surgeons in the country – are known for innovative techniques and excellent outcomes.
We consider your quality of life one of our top priorities. That’s why we offer the most advanced surgical methods for vaginal cancer, including procedures that allow some women to keep the ability to have children.
We’re constantly researching newer, safe, more-advanced vaginal cancer treatments. This translates to a number of clinical trials of new treatments for vaginal cancer.